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Antioxidant BHT 264
CAS:128-37-0
Purity:99%
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Entecavir is white to off-white/yellow crystalline powder, while it's Molecular Formula is C12H15N5O3. Entecavir is a new generation of guanine nucleoside analogues oral medicine for treatment of hepatitis B virus infection in, mainly for the treatment of adult patients with viral replication activity and serum transaminase continued to increase, or liver tissue for pathological activity of chronic hepatitis B, is currently down virus the fastest and the most powerful, the mutation rate lowest nucleoside analogues.
The CAS number of Entecavir is 142217-69-4.
More information of Entecavir 142217-69-4 are:
Synonyms |
2-amino-9-[(3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;ETV;6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-;2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;SQ 34676;BMS 200475;Baraclude;6H-Purin-6-one,2-amino-1,9-dihydro-9- [(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2- methylenecyclopentyl]-;Taizhou hikong chemical sell Entecavir;Entecavi;Enteca;Entecavir(monohydrate)--Crude Product; |
CAS Number |
142217-69-4 |
Molecular Formula |
C12H15N5O3 |
Molecular Weight |
277.283 |
Density |
1.81 g/cm3 |
Melting Point |
249-252 °C |
Boiling Point |
734.2 °C at 760 mmHg |
Flash Point |
397.9 °C |
HS CODE |
29339900 |
PSA |
130.05000 |
LogP |
-0.24660 |
Pka |
14.22±0.60(Predicted) |
Entecavir is a cyclopentyl guanosine analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection, and it is the third nucleoside or nucleotide analog to be marketed for this indication. Lamivudine, a deoxythiacytosine analog, and adefovir dipivoxil, a nucleotide analog, have been marketed since 1998 and 2002, respectively. Entecavir and adefovir are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections.
InChI:InChI=1/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8+/m0/s1
Articles related to Entecavir:
Article |
Source |
A novel and efficient synthesis of Entecavir |
Liu, Xiaoyu,Jiao, Xiaozhen,Wu, Qian,Tian, Chengsen,Li, Renze,Xie, Ping , p. 3805 - 3807 (2012) |
Novel preparation method and intermediates of entecavir |
- , (2021/04/10) |
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