Entecavir

  • CAS:142217-69-4
  • MF:C12H15N5O3
  • Purity:99%
  • Molecular Weight:277.283
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Product Details

  • CAS: 142217-69-4
  • MF: C12H15N5O3
  • Appearance: white to off-white/yellow crystalline powder
  • Manufacturer supply good quality Entecavir 142217-69-4 with stock We supply high quality Entecavir (CAS 142217-69-4), in stock, factory directly supply to clients, lower prices, more competitiveness.

    What is the Entecavir ?

    Entecavir is white to off-white/yellow crystalline powder, while it's Molecular Formula is C12H15N5O3. Entecavir is a new generation of guanine nucleoside analogues oral medicine for treatment of hepatitis B virus infection in, mainly for the treatment of adult patients with viral replication activity and serum transaminase continued to increase, or liver tissue for pathological activity of chronic hepatitis B, is currently down virus the fastest and the most powerful, the mutation rate lowest nucleoside analogues.

    What is the CAS number for Entecavir ?

    The CAS number of Entecavir is 142217-69-4.

    More information of Entecavir 142217-69-4 are:

    Synonyms

    2-amino-9-[(3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;ETV;6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-;2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;SQ 34676;BMS 200475;Baraclude;6H-Purin-6-one,2-amino-1,9-dihydro-9- [(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2- methylenecyclopentyl]-;Taizhou hikong chemical sell Entecavir;Entecavi;Enteca;Entecavir(monohydrate)--Crude Product;

    CAS Number

    142217-69-4

    Molecular Formula

    C12H15N5O3

    Molecular Weight

    277.283

    Density

    1.81 g/cm3

    Melting Point

    249-252 °C

    Boiling Point

    734.2 °C at 760 mmHg

    Flash Point

    397.9 °C

    HS CODE

    29339900

    PSA

    130.05000

    LogP

    -0.24660

    Pka

    14.22±0.60(Predicted)

    What is Entecavir (142217-69-4) used for?

    Entecavir is a cyclopentyl guanosine analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection, and it is the third nucleoside or nucleotide analog to be marketed for this indication. Lamivudine, a deoxythiacytosine analog, and adefovir dipivoxil, a nucleotide analog, have been marketed since 1998 and 2002, respectively. Entecavir and adefovir are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections.

    InChI:InChI=1/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8+/m0/s1

    Articles related to Entecavir:

    Article

    Source

    A novel and efficient synthesis of Entecavir

    Liu, Xiaoyu,Jiao, Xiaozhen,Wu, Qian,Tian, Chengsen,Li, Renze,Xie, Ping

    , p. 3805 - 3807 (2012)

    Novel preparation method and intermediates of entecavir

    -

    , (2021/04/10)

    How to get the best price on Entecavir?

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    Antioxidant BHT 264

    CAS:128-37-0

    Purity:99%

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