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Quality products make an important contribution to long-term revenue and profitability. China cas 1078-21-3 manufacturer wholesale 4-Amino-3-phenylbutanoic acid at affordable price
4-amino-3-phenylbutanoic acid (cas# 1078-21-3) is a GABAA receptor agonist, used for treatment of disorders influenced by dysfunction of pancreatic β cells and also used in combination with other agents.
4-nitro-3-phenyl butanoic acid
4-amino-3-phenylbutanoic acid
| Conditions | Yield |
|---|---|
|
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 60 ℃;
under 45004.5 Torr;
|
98% |
4-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)butanamide
4-amino-3-phenylbutanoic acid
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
at 130 ℃;
for 24h;
Sealed tube;
|
95% |
The CAS number of 4-Amino-3-phenylbutanoic acid is 1078-21-3.
More information of 4-Amino-3-phenylbutanoic acid 1078-21-3 are:
|
CAS Number |
1078-21-3 |
|
Density |
1.161 g/cm3 |
|
Melting Point |
194.0-202 °C |
|
Boiling Point |
327.8 °C at 760 mmHg |
|
Flash Point |
152.1 °C |
|
Vapor Pressure |
7.98E-05mmHg at 25°C |
|
Refractive Index |
1.5710 (estimate) |
|
HS CODE |
2922499990 |
|
PSA |
63.32000 |
|
LogP |
2.70590 |
|
Pka |
4.10±0.10(Predicted) |
Synonyms for 4-Amino-3-phenylbutanoic acid 1078-21-3:Hydrocinnamicacid, b-(aminomethyl)- (6CI,7CI,8CI);3-Phenyl-4-aminobutanoic acid;4-Amino-3-phenylbutyricacid;DL-4-Amino-3-phenylbutanoic acid;DL-b-Phenyl-g-aminobutyric acid;Fenibut;Fenigam;Fenigama;P-GABA;PhGABA;Phenibut;Phenigam;Phenybut;Phenygam;b-Phenyl-GABA;b-Phenyl-g-aminobutyricacid;g-Amino-b-phenylbutyric acid;
The chemical formula of 4-Amino-3-phenylbutanoic acid is C10H13NO2 which containing 10 Carbon atoms,13 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of 4-Amino-3-phenylbutanoic acid is 179.219.
Phenibut, also known as fenibut, phenigamma, and beta-phenyl-gamma-aminobutyric acid, is a derivative of the neurotransmitter GABA. It was developed in Russia,and there it has been used clinically since the 1960s to treat anxiety and related conditions，including insomnia(Lapin，2001). Phenibut has anxiolytic properties and is commonlycompared to benzodiazepines and baclofen.Structurally，phenibut issimilar to GABA, with the addition of the phenyl ring. This allows thecompound to more easily cross the blood-brain barrier, but also changesits activity profile (Shulgina,1986). Scientific studies demonstrate that phenibut can be safely used to treat anxiety, depression,epilepsy, speech disorders, and insomnia.
InChI:InChI=1/C10H13NO2.ClH/c11-7-9(6-10(12)13)8-4-2-1-3-5-8;/h1-5,9H,6-7,11H2,(H,12,13);1H
Relevant articles related to 4-Amino-3-phenylbutanoic acid:
|
Article |
Source |
|
Rhodium-catalyzed asymmetric hydrogenation of β-cyanocinnamic esters with the assistance of a single hydrogen bond in a precise position |
Li, Xiuxiu,You, Cai,Yang, Yusheng,Yang, Yuhong,Li, Pan,Gu, Guoxian,Chung, Lung Wa,Lv, Hui,Zhang, Xumu , p. 1919 - 1924 (2018) |
|
Catalytic Intermolecular Carboamination of Unactivated Alkenes via Directed Aminopalladation |
Liu, Zhen,Wang, Yanyan,Wang, Zichen,Zeng, Tian,Liu, Peng,Engle, Keary M. supporting information, p. 11261 - 11270 (2017/08/22) |
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