What is the Tadalafil?

Tadalafil is white to off-white cyrstalline solid, while it's Molecular Formula is C22H19N3O4. white to off-white cyrstalline solid Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

What is the CAS number for Tadalafil?

The CAS number of Tadalafil is 171596-29-5.

What is Tadalafil (171596-29-5) used for?

Tadalafil (market name “Cialis” or “Adcirca”) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. The mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia.InChI:InChI=1/C22H23N3O3/c1-24-8-9-25-17(22(24)26)11-15-14-4-2-3-5-16(14)23-20(15)21(25)13-6-7-18-19(10-13)28-12-27-18/h2-7,10,15,17,20-21,23H,8-9,11-12H2,1H3/t15?,17-,20?,21-/m1/s1

What is the Tadalafil?

Tadalafil is white to off-white cyrstalline solid, while it's Molecular Formula is C22H19N3O4. white to off-white cyrstalline solid Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

What is the CAS number for Tadalafil?

The CAS number of Tadalafil is 171596-29-5.

What is Tadalafil (171596-29-5) used for?

Tadalafil (market name “Cialis” or “Adcirca”) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. The mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia.InChI:InChI=1/C22H23N3O3/c1-24-8-9-25-17(22(24)26)11-15-14-4-2-3-5-16(14)23-20(15)21(25)13-6-7-18-19(10-13)28-12-27-18/h2-7,10,15,17,20-21,23H,8-9,11-12H2,1H3/t15?,17-,20?,21-/m1/s1

Tadalafil

CAS：171596-29-5
MF：C₂₂H₁₉N₃O₄
Purity：99%
Molecular Weight：389.411

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Product Details

CAS： 171596-29-5

MF： C₂₂H₁₉N₃O₄

Appearance： white to off-white cyrstalline solid

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Molecular Formula:C22H19N3O4
Molecular Weight:389.411
Appearance/Colour:white to off-white cyrstalline solid
Vapor Pressure:5.29E-13mmHg at 25°C
Melting Point:298-300 °C
Refractive Index:1.705
Boiling Point:679.1 °C at 760 mmHg
PKA:16.68±0.40(Predicted)
Flash Point:364.5 °C
PSA：74.87000
Density:1.51 g/cm³
LogP:2.08710

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