Antioxidant BHT 264
CAS:128-37-0
Purity:99%
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Quality products make an important contribution to long-term revenue and profitability. Top quality factory supply 224785-91-5 Vardenafil hydrochloride at low price
vardenafil hydrochloride is a selective phsphodiesterase type 5 (pde5) inhibitor that is used as a urological agent in the treatment of erectile dysfunction.
The CAS number of Vardenafil hydrochloride is 224785-91-5.
More information of Vardenafil hydrochloride 224785-91-5 are:
CAS Number |
224785-91-5 |
Melting Point |
214-216 °C |
Boiling Point |
692.2 °C at 760 mmHg |
Flash Point |
372.5 °C |
Vapor Pressure |
5.17E-19mmHg at 25°C |
HS CODE |
2933299090 |
PSA |
121.28000 |
LogP |
3.82900 |
Synonyms for Vardenafil hydrochloride 224785-91-5:Piperazine,1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-,monohydrochloride (9CI);Levitra;
The chemical formula of Vardenafil hydrochloride is C23H33ClN6O4S which containing 23 Carbon atoms,33 Hydrogen atoms,1 Chlorine atoms,6 Nitrogen atoms,4 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of Vardenafil hydrochloride is 525.06.
Vardenafil was the second agent to be marketed and had the advantage that its onset time was not reduced by taking the medication on a full stomach . It is 30 times more potent as an inhibitor of PDE5 (mean IC50, 3.9 nM) than sildenafil and 10 times more potent than tadalafil, with a greater selectivity (>1,000 times) for human PDE5 than for human PDE2, PDE3, and PDE4 and moderate selectivity (>80 times) for PDE1. The PDE inhibitory selectivity and both the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Vardenafil specifically inhibited the hydrolysis of cGMP by PDE5, with an IC50 of 0.7 nM (sildenafil 6.6 nM). The IC50 of vardenafil for PDE1 was 180 nM, for PDE6 11 nM, and for PDE2, PDE3 and PDE4 more than 1,000 nM.
InChI:InChI=1/C23H32N6O4S.2ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);2*1H
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