What is the 11-Aminoundecanoic acid?

11-Aminoundecanoic acid is White crystalline powder, while it's Molecular Formula is C11H23NO2. White crystalline powder 11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1''as matrix metalloproteinase inhibitors.

What is the CAS number for 11-Aminoundecanoic acid?

The CAS number of 11-Aminoundecanoic acid is 2432-99-7.

What is 11-Aminoundecanoic acid (2432-99-7) used for?

Aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Aminoundecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.InChI:InChI=1/C11H23NO2/c1-2-3-4-5-6-7-8-9-10(12)11(13)14/h10H,2-9,12H2,1H3,(H,13,14)

What is the 11-Aminoundecanoic acid?

11-Aminoundecanoic acid is White crystalline powder, while it's Molecular Formula is C11H23NO2. White crystalline powder 11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1''as matrix metalloproteinase inhibitors.

What is the CAS number for 11-Aminoundecanoic acid?

The CAS number of 11-Aminoundecanoic acid is 2432-99-7.

What is 11-Aminoundecanoic acid (2432-99-7) used for?

Aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Aminoundecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.InChI:InChI=1/C11H23NO2/c1-2-3-4-5-6-7-8-9-10(12)11(13)14/h10H,2-9,12H2,1H3,(H,13,14)

11-Aminoundecanoic acid

CAS：2432-99-7
MF：C₁₁H₂₃NO₂
Purity：99%
Molecular Weight：201.309

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Product Details

CAS： 2432-99-7

MF： C₁₁H₂₃NO₂

Appearance： White crystalline powder

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Molecular Formula:C11H23NO2
Molecular Weight:201.309
Appearance/Colour:White crystalline powder
Vapor Pressure:8.39E-05mmHg at 25°C
Melting Point:188-191 °C(lit.)
Refractive Index:1.468
Boiling Point:334.87 °C at 760 mmHg
PKA:4.78±0.10(Predicted)
Flash Point:156.324 °C
PSA：63.32000
Density:0.965 g/cm³
LogP:3.24090

11-Aminoundecanoic acid(Cas 2432-99-7) Usage

Preparation	ω-Aminoundecanoic acid is normally prepared from castor oil (glycerol triricinoleate). Firstly the castor oil is subjected to methanolysis to yield the methyl ester of ricinoleic acid and then the following route is used: In the first step, the pyrolysis of methyl ricinoleate is carried out at about 500°C; the principal products are n-heptaldehyde and methyl undecylenate. The latter is hydrolysed to give undecylenic acid which is treated with hydrogen bromide in a non-polar solvent in the presence of a peroxide. Under these conditions, reverse Markownikoff addition occurs and the main product is ω-bromoundecanoic acid. This product is then treated with ammonia to give ω-aminoundecanoic acid, which is a crystalline solid, m.p. 189°C.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	11-Aminoundecanoic acid is incompatible with strong oxidizing agents, strong acids and strong bases.
Fire Hazard	Flash point data for 11-Aminoundecanoic acid are not available; however, 11-Aminoundecanoic acid is probably combustible.
Flammability and Explosibility	Nonflammable
Safety Profile	Poison by ingestion. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

InChI:InChI=1/C11H23NO2/c1-2-3-4-5-6-7-8-9-10(12)11(13)14/h10H,2-9,12H2,1H3,(H,13,14)

2432-99-7 Relevant articles

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2432-99-7 Process route

: C₃₆H₆₀O₃₀*C₁₁H₂₃NO₂

: 2432-99-7,25587-80-8,84029-94-7
11-aminoundecanoic acid

: 10016-20-3
alpha cyclodextrin

Conditions

Conditions	Yield
In water; at 25 ℃; Equilibrium constant; pH 4.7;
In water-d2; at 24.85 ℃; pH=7.3; Further Variations:; Temperatures; pH-values; Equilibrium constant;

: 854401-56-2
10-cyano-9-decenoate

: 2432-99-7,25587-80-8,84029-94-7
11-aminoundecanoic acid

Conditions

Conditions	Yield
With ammonia; hydrogen; In propan-1-ol; at 110 ℃; for 2h; under 30003 Torr; Autoclave; Inert atmosphere;
With hydrogen; at 100 ℃; for 5h; under 22502.3 Torr; Reagent/catalyst; Pressure;	6.3 g