1-Methylpyrrolidine

  • CAS:120-94-5
  • MF:C5H11N
  • Purity:99%
  • Molecular Weight:85.149
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Product Details

  • CAS: 120-94-5
  • MF: C5H11N
  • Appearance: clear to yellow liquid
  • Chemical plants supply high-quality 1-Methylpyrrolidine 120-94-5 in bulk

    • Molecular Formula:C5H11N
    • Molecular Weight:85.149
    • Appearance/Colour:clear to yellow liquid 
    • Vapor Pressure:79.6mmHg at 25°C 
    • Melting Point:-90 °C 
    • Refractive Index:1.425 
    • Boiling Point:82.1 °C at 760 mmHg 
    • PKA:10.32(at 25℃) 
    • Flash Point:-7 °F 
    • PSA:3.24000 
    • Density:0.853 g/cm3 
    • LogP:0.64990 

    1-Methylpyrrolidine(Cas 120-94-5) Usage

    Preparation

    n-methylpyrrolidine was successfully synthesized in an aqueous medium by using methylamine and 1,4-dibromobutane in the presence of catalyst k2co3 at a moderated temperature. here, n-methylpyrrolidine was firstly synthesized via the green chemistry process, in which both the water solvent and potassium carbonate catalyst were inexpensive and environmentally friendly. also, the reaction temperature was quite moderated at 90°C.green organic synthesis of n-methylpyrrolidine

    Hazard

    Flammable, dangerous fire risk. Irritant toskin and eyes.

    Flammability and Explosibility

    Highlyflammable

    Safety Profile

    Poison by intraperitoneal and intravenous routes. This material is strongly alkaline. Liquid and vapors are corrosive to the skin, eyes, or mucous membranes. A very dangerous fire hazard; keep away from sparks, heat sources, and powerful oxidizers. Keep in closed containers. To fight fire, use alcohol foam. When heated to decomposition it emits highly toxic fumes of NOx.

    InChI:InChI=1/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3/p+1

    120-94-5 Relevant articles

    -

    Nakajima

    , p. 1218 (1961)

    -

    -

    Bourns et al.

    , p. 1,4 (1963)

    -

    -

    Searles et al.

    , p. 4917,4918 (1956)

    -

    The 4-[N-methyl-N-(2,2,2-trifiuoroacetyl)amino]butyl group as an alternative to the 2-cyanoethyl group for phosphate protection in the synthesis of oligodeoxyribonucleotides

    Wilk, Andrzej,Grajkowski, Andrzej,Phillips, Lawrence R.,Beaucage, Serge L.

    , p. 7515 - 7522 (1999)

    The 4-[N-methyl-N-(2,2,2-trifluoroacetyl...

    Gas-Phase Elimination Kinetics of (Dimethylamino)alkyl Acetates. The Ion-Pair Mechanism through Neighboring Group Participation.

    Chuchani, Gabriel,Rotinov, Alexandra,Dominguez, Rosa M.,Gonzalez, Neil

    , p. 4157 - 4160 (1984)

    The gas-phase elimination kinetics of so...

    One-pot synthesis of: N -methylpyrrolidine (NMPD) using Cu- and Ni-modified ZSM-5 as an efficient catalyst

    Long, Yan,Wang, Peixue,Fei, Yuqing,Zhou, Dawei,Liu, Shimin,Deng, Youquan

    , p. 141 - 148 (2019)

    In this study, a green, efficient and lo...

    Poisoning and Reuse of Supported Precious Metal Catalysts in the Hydrogenation of N-Heterocycles Part?I: Ruthenium-Catalysed Hydrogenation of 1-Methylpyrrole

    Heged?s, László,Sz?ke-Molnár, Kristóf,Sajó, István E.,Srankó, Dávid Ferenc,Schay, Zoltán

    , p. 1939 - 1950 (2018)

    Abstract: Poisoning phenomena of heterog...

    Powering Artificial Enzymatic Cascades with Electrical Energy

    Al-Shameri, Ammar,Apfel, Ulf-Peter,Lauterbach, Lars,Nestl, Bettina M.,Petrich, Marie-Christine,junge Puring, Kai

    , p. 10929 - 10933 (2020)

    We have developed a scalable platform th...

    Preparation and GC-MS-Identification of N-Methyl-Δ3-pyrroline

    Mahboobi, Siavosh,Fischer, Erich Chr.,Eibler, Ernst,Wiegrebe, Wolfgang

    , p. 423 - 424 (1988)

    The preparation of N-methyl-Δ3-pyrroline...

    Highly economical and direct amination of sp3carbon using low-cost nickel pincer catalyst

    Brandt, Andrew,Rangumagar, Ambar B.,Szwedo, Peter,Wayland, Hunter A.,Parnell, Charlette M.,Munshi, Pradip,Ghosh, Anindya

    , p. 1862 - 1874 (2021/01/20)

    Developing more efficient routes to achi...

    Zirconium-hydride-catalyzed site-selective hydroboration of amides for the synthesis of amines: Mechanism, scope, and application

    Han, Bo,Jiao, Haijun,Wu, Lipeng,Zhang, Jiong

    , p. 2059 - 2067 (2021/09/02)

    Developing mild and efficient catalytic ...

    Electrochemical Activation of Diverse Conventional Photoredox Catalysts Induces Potent Photoreductant Activity**

    Chernowsky, Colleen P.,Chmiel, Alyah F.,Wickens, Zachary K.

    supporting information, p. 21418 - 21425 (2021/08/25)

    Herein, we disclose that electrochemical...

    A Lewis Base Nucleofugality Parameter, NFB, and Its Application in an Analysis of MIDA-Boronate Hydrolysis Kinetics

    García-Domínguez, Andrés,Gonzalez, Jorge A.,Leach, Andrew G.,Lloyd-Jones, Guy C.,Nichol, Gary S.,Taylor, Nicholas P.

    supporting information, (2022/01/04)

    The kinetics of quinuclidine displacemen...

    120-94-5 Process route

    C<sub>5</sub>H<sub>11</sub>N*C<sub>6</sub>H<sub>5</sub>NO<sub>3</sub>

    C5H11N*C6H5NO3

    1-Methylpyrrolidine
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    Conditions
    Conditions Yield
    In 1,4-dioxane; at 24.84 ℃; Equilibrium constant; Ionic liquid;
    1-methyl-1-phenethyl-pyrrolidinium; iodide

    1-methyl-1-phenethyl-pyrrolidinium; iodide

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    styrene

    Conditions
    Conditions Yield
    Nachfolgende Destillation unter Normaldruck;

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    Purity:99%

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