Antioxidant BHT 264
CAS:128-37-0
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Manufacturer Sells Best Quality Ofloxacin 82419-36-1 with stock We supply high quality Ofloxacin (CAS 82419-36-1), in stock, factory directly supply to clients, lower prices, more competitiveness.
Ofloxacin is Off-white solid, while it's Molecular Formula is C18H20FN3O4. Ofloxacin is a fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).
The CAS number of Ofloxacin is 82419-36-1.
More information of Ofloxacin 82419-36-1 are:
Synonyms |
Exocin;Floxin (TN);HOE 280;(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;Tarivid;DL-8280;Visiren;Prestwick_600;DL 8280;Ocuflox;OFX;Ofloxacin (JP14/USP);ORF 18489;Floxin;OFLX;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6- carboxylic acid,9-fluoro-2,3-dihydro-3- methyl-10-(4-methyl-1-piperazinyl)-7-oxo-;Ofloxacin (COS);Levoflxacin; |
CAS Number |
82419-36-1 |
Molecular Formula |
C18H20FN3O4 |
Molecular Weight |
361.373 |
Density |
1.48 g/cm3 |
Melting Point |
270-275 °C |
Boiling Point |
571.5 °C at 760 mmHg |
Flash Point |
299.4 °C |
HS CODE |
29349990 |
PSA |
75.01000 |
LogP |
1.54690 |
Pka |
5.19±0.40(Predicted) |
Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that prevents supercoiling of bacterial chromosomes by DNA gyrase. It is active against Gram-positive and Gram-negative bacteria with MIC90s ranging from 0.39 to 3.13 μg/ml for clinical isolates of S. aureus, S. epidermidis, S. pyogenes, and S. faecalis and ≤0.78 μg/ml for N. gonorrhoeae and various species of Enterobacteriaceae. Ofloxacin is active in vivo, with ED50 values ranging from 0.7 to 75.1 mg/kg in infected mice. Formulations containing ofloxacin have been used to treat urinary tract infections, gonorrhea, prostatitis, and gastroenteritis.
InChI:InChI=1/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
Articles related to Ofloxacin:
Article |
Source |
Nano-Fe3 O4@ZrO2-SO3 H as highly efficient recyclable catalyst for the green synthesis of fluoroquinolones |
Nakhaei, Ahmad,Ramezani, Shirin,Shams-Najafi, Sayyed Jalal,Farsinejad, Sadaf , p. 739 - 746 (2018/09/26) |
Levofloxacin and ofloxacin preparation method |
- Paragraph 0039-0042, (2017/09/01) |
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