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Dexoxadrol

  • CAS：4741-41-7
  • MF：C22H28ClNO2
  • Purity：99%
  • Molecular Weight：309.408
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Product Details

  • CAS： 4741-41-7
  • MF： C22H28ClNO2

    • Perfect Factory Offer Excellent quality Dexoxadrol 4741-41-7 with Safe Shipping

    • Molecular Formula:C22H28ClNO2
    • Molecular Weight:309.408
    • Vapor Pressure:5.26E-08mmHg at 25°C 
    • Refractive Index:1.5614 (estimate) 
    • Boiling Point:441.9°C at 760 mmHg 
    • Flash Point:187.1°C 
    • PSA：30.49000 
    • Density:1.13g/cm3 
    • LogP:3.77400 

    Dexoxadrol(Cas 4741-41-7) Usage

    InChI:InChI=1/C20H23NO2/c1-3-9-16(10-4-1)20(17-11-5-2-6-12-17)22-15-19(23-20)18-13-7-8-14-21-18/h1-6,9-12,18-19,21H,7-8,13-15H2/t18-,19+/m0/s1

    4741-41-7 Relevant articles

    A concise diastereoselective approach to (+)-dexoxadrol, (-)-epi-dexoxadrol, (-)-conhydrine and (+)-lentiginosine from (-)-pipecolinic acid

    Bhat, Chinmay,Tilve, Santosh G.

    , p. 10876 - 10883 (2014/01/06)

    A new diastereoselective pathway for the...

    An expeditious method for the first asymmetric synthesis of dexoxadrol from the chiral pool

    Etayo, Pablo,Badorrey, Ramón,Díaz-De-Villegas, María D.,Gálvez, José A.,López-Ram-De-Víu, Pilar

    experimental part, p. 1775 - 1778 (2010/10/20)

    A new, straightforward and high-yielding...

    Synthesis and SAR studies of chiral non-racemic dexoxadrol analogues as uncompetitive NMDA receptor antagonists

    Banerjee, Ashutosh,Schepmann, Dirk,K?hler, Jens,Würthwein, Ernst-Ulrich,Wünsch, Bernhard

    experimental part, p. 7855 - 7867 (2011/02/22)

    A series of chiral non-racemic dexoxadro...

    4741-41-7 Process route

    dimethoxydiphenylmethane
    2235-01-0

    dimethoxydiphenylmethane

    (βS,2S)-β-hydroxypiperidin-2-ethanol
    117994-55-5

    (βS,2S)-β-hydroxypiperidin-2-ethanol

    dexoxadrol
    4741-41-7

    dexoxadrol

    Conditions
    Conditions Yield
    With toluene-4-sulfonic acid; In isopropyl alcohol; for 1h; Reflux;
    		60%
    benzyl (2S)-2-[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate
    1247664-50-1

    benzyl (2S)-2-[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate

    dexoxadrol
    4741-41-7

    dexoxadrol

    Conditions
    Conditions Yield
    With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; under 760.051 Torr;
    		99%

    4741-41-7 Upstream products

    • 1247664-50-1
      1247664-50-1

      benzyl (2S)-2-[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate

    • 1257901-09-9
      1257901-09-9

      benzyl (2S,4R)-2-[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]-4-hydroxypiperidine-1-carboxylate

    • 1514644-66-6
      1514644-66-6

      (S)-benzyl-2-vinylpiperidine-1-carboxylate

    • 2235-01-0
      2235-01-0

      dimethoxydiphenylmethane

    4741-41-7 Downstream products

    • 631-06-1
      631-06-1

      (+)-dexoxadrol hydrochloride

    • 23239-37-4
      23239-37-4

      Etoxadrol hydrochloride

    • 117019-54-2
      117019-54-2

      Epietoxadrol hydrochloride

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    Purity:99%

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