Antioxidant BHT 264
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Purity:99%
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Reputable manufacturer supply Megestrol Acetate 595-33-5 in stock with high standard We supply high quality Megestrol acetate (CAS 595-33-5), in stock, factory directly supply to clients, lower prices, more competitiveness.
Megestrol acetate is Crystalline Solid, while it's Molecular Formula is C24H32O4. Megestrol acetate (Megace), a semi-synthetic progestational steroid, is the most effective known appetite stimulant at present. Previously used in patients with cancer and acquired immunodeficiency syndrome, only a few studies have considered the applicability of this drug in malnourished older persons. Megestrol acetate is useful if profound anorexia is the main manifestation of cachexia and if expected survival is weeks to months. Megace has been shown to significantly increase appetite, but not survival. In patients with a shorter predicted survival, a brief course of corticosteroids may be useful to stimulate appetite and have positive effects on nausea, pain, and asthenia.
The CAS number of Megestrol acetate is 595-33-5.
More information of Megestrol acetate 595-33-5 are:
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Synonyms |
Megace ES;Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-;Ovarid;Megace;Ovaban (Veterinary);Megeron;6-Methyl-delta4,6-pregnadien-17alpha-ol-3,20-dione acetate;6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone;Megace (TN);SC 10363;Megestryl acetate;Pregna-4,6-diene-3, 20-dione, 17-hydroxy-6-methyl-, acetate;Pallace;Ovaban;S4;6-Methyl-17-alpha-hydroxy-delta(sup 6)-progesterone acetate;SC-10363;SC10363;Niagestin;Progesterone, 6-dehydro-17-hydroxy-6-methyl-, acetate;6-Methyl-delta(sup 4,6)-pregnadien-17-alpha-ol-3,20-dione acetate;Megestrol acetate [USAN];17alpha-Acetoxy-6-dehydro-6-methylprogesterone;Megestrol acetate (USAN);Megestat;6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;Megestrol acetole [Progestins];6-MethleneProgesterone Acetate;Pregna-4,6-diene-3, 20-dione, 17- (acetyloxy)-6-methyl-;BDH 1298; |
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CAS Number |
595-33-5 |
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Molecular Formula |
C24H32O4 |
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Molecular Weight |
384.516 |
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Density |
1.15 g/cm3 |
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Melting Point |
214 °C |
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Boiling Point |
507.1 °C at 760 mmHg |
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Flash Point |
218.5 °C |
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HS CODE |
29372390 |
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PSA |
60.44000 |
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LogP |
4.57530 |
Megestrol Acetate is the acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic and antineoplastic activity. It is frequently used in the treatment of patients with metastatic breast cancer. It is generally well tolerated, except that it may cause undesirable weight gain. Subsequently, it was shown that megestrol acetate produced weight gain in a variety of cachectic cancer patients. Significant reduction inserum levels of IL-1a and b,IL-2,IL-6, and TNF-o were observed in cancer patientstreated with megestrol acetate which may bear on the mechanism of improved appetite and body weight gain.It has also been postulated that the effect is, at least in part,mediated by NPY,a potent central appetite stimulant.
InChI:InChI=1/C23H30O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h5-6,13,18-20H,7-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1
Articles related to Megestrol acetate:
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Article |
Source |
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The preparation method of the megestrol (by machine translation) |
- Paragraph 0009; 0012; 0014; 0016, (2018/01/13) |
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Anti-Claudin 3 Monoclonal Antibody and Treatment and Diagnosis of Cancer Using the Same |
- , (2010/05/13) |
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